Braine-l&#039;Alleud / en Advancing Our Gene Therapy Journey /about-ucb/magazine/detail/article/advancing-our-gene-therapy-journey <span>Advancing Our Gene Therapy Journey</span> <div class="field field--name-field-newsroom-author-title field--type-string field--label-above field__items"> Christophe Dumont, Genesis Project </div> <span><span lang about="/user/8671" typeof="schema:Person" property="schema:name" datatype content="Nathalie.Vandenbruaene@ucb.com">Vandenbruaene …</span></span> <span><time datetime="2024-07-12T08:49:46+02:00" title="Friday 12 July 2024 - 08:49">Fri 12/07/2024 - 08:49</time> </span> <div class="field field--name-field-newsroom-author-image field--type-entity-reference field--label-above field__items"> <article class="media media--type-image media--view-mode-default"> <div class="field field--name-image field--type-image field--label-hidden field__items"> <img loading="lazy" src="/sites/default/files/styles/ucb_header_image/public/2024-07/christophe_dumont.jpg.webp?itok=rRDhNIqk" width="135" height="137" typeof="foaf:Image"> </div> </article> </div> <div class="field field--name-field-newsroom-content field--type-text-long field--label-above field__items"> <p><br>I am thrilled to share the latest progress on our groundbreaking gene therapy facility in Braine-l'Alleud, Wallonia, Belgium. The exterior of the facility is now complete, and we are currently moving forward with the “Fit Out” activities. The first equipment is delivered and already in place. This marks a significant milestone in our journey towards revolutionizing disease treatment through advanced gene therapy.</p><article data-quickedit-entity-id="media/46067" class="media media--type-image media--view-mode-default"> <div class="field field--name-image field--type-image field--label-hidden field__items"> <img loading="lazy" src="/sites/default/files/styles/ucb_header_image/public/2024-07/braine-lalleud_ucb_genesis_vue_1_231129_1_0.jpg.webp?itok=jpwyJQEI" width="800" height="585" typeof="foaf:Image"> </div> </article> <p>&nbsp;</p><p>Why is this project important? For ֳ, it means opening new opportunities to discover and develop cures for the people we serve. For me, it's deeply personal. People living with severe diseases are at the heart of everything we do, and every morning, I’m motivated by the thought that this facility could one day help my loved ones.</p><p>Beyond the personal and corporate impact, this state-of-the-art facility, representing a substantial investment in Belgium, is designed to be both innovative and environmentally sustainable. It will significantly enhance our development and manufacturing capabilities, reinforcing our existing teams in Braine-l’Alleud (Belgium), Leuven (Belgium), Boston (USA), and Durham (UK).</p><p>Our new facility will allow us to have complete ownership of our chemistry, manufacturing, and controls (CMC) capabilities. This will enable us to be more agile in responding to new trends and opportunities, and more scalable to meet the unmet needs of patients. The efficient clinical manufacturing capability will ensure we maintain high standards of speed, scalability, and quality as we bring our gene therapy research projects to patients.</p><h2>Building Gene Therapy Skills</h2><p>In addition to the physical construction of the facility, we are also committed to developing our skills and expertise in gene therapy and more largely bio-related fields. This field offers a wealth of opportunities for both current employees and new hires. We are excited to announce that the novel facility will create over 100 new, highly skilled jobs. We are actively seeking talented, inspired, and passionate individuals who are eager to join us in improving lives through innovative therapies.</p><p>If you have a passion for pushing the boundaries of what’s possible and making a real difference in patients' lives, we invite you to join our dynamic team. Exciting positions and unique opportunities await you at our cutting-edge facility.</p><h2>Join Us on This Exciting Journey</h2><p>The completion of this facility will expand ֳ's innovation footprint, which includes sites in Belgium, Japan, Switzerland, Germany, the US, and the UK. It will support our ambition for carbon neutrality by implementing the latest technologies and achieving BREEAM (Building Research Establishment Environmental Assessment Method certification), aiming to drastically reduce both resource consumption and waste production.</p><p>I look forward to the exciting advancements and innovations this new facility will bring. Together, we can transform the future of disease treatment and make a lasting impact on patients' lives. For more details, please visit our <a class="no class" href="https://careers.ucb.com/global/en/ucb-gene-therapy-" target="_blank">career page</a>.</p><h2><a href="https://careers.ucb.com/global/en/ucb-gene-therapy-" target="_blank">Join our team</a></h2><article data-quickedit-entity-id="media/46066" class="media media--type-image media--view-mode-default"> <div class="field field--name-image field--type-image field--label-hidden field__items"> <img loading="lazy" src="/sites/default/files/styles/ucb_header_image/public/2024-07/20240710_ucb_001.jpg.webp?itok=Ra_7XYp_" typeof="foaf:Image"> </div> </article> </div> <div class="field field--name-field-newsroom-category field--type-entity-reference field--label-above field__items"> <a href="/taxonomy/term/1907" hreflang="en">about ucb</a> </div> <div class="field field--name-field-newsroom-tags field--type-entity-reference field--label-above field__items"> <a href="/taxonomy/term/1866" hreflang="en"> Gene Therapy</a> <a href="/taxonomy/term/1352" hreflang="en"> innovation </a> <a href="/taxonomy/term/5661" hreflang="en">Braine-l'Alleud</a> </div> <div> <div class="comments-wrapper"> <div class="comment-area"> <h2 class="red">Leave a Comment</h2> <drupal-render-placeholder callback="comment.lazy_builders:renderForm" arguments="0=node&amp;1=15050&amp;2=field_newsroom_askexpert&amp;3=ask_expert" token="9mjiZqy7cZ5tJuXWbVBEnexAs5PgnDmyaJqJBIvIYJI"></drupal-render-placeholder> <span class="toggle-form js-toggle-form"></span> </div> </div> </div> <span class="a2a_kit a2a_kit_size_16 addtoany_list" data-a2a-url="/about-ucb/magazine/detail/article/advancing-our-gene-therapy-journey" data-a2a-title="Advancing Our Gene Therapy Journey"><a class="a2a_dd addtoany_share" href="https://www.addtoany.com/share#url=https%3A%2F%2Fwww.ucb.com%2Fabout-ucb%2Fmagazine%2Fdetail%2Farticle%2Fadvancing-our-gene-therapy-journey&amp;title=Advancing%20Our%20Gene%20Therapy%20Journey"></a><a class="a2a_button a2a_button_facebook"><img src="/themes/custom/ucb_premier/images/a2a/facebook-icon.svg" width="16" height="16" border="0" alt="linkedin"></a><a class="a2a_button a2a_button_linkedin"><img src="/themes/custom/ucb_premier/images/a2a/linkedin-icon.svg" width="16" height="16" border="0" alt="linkedin"></a><a class="a2a_button a2a_button_twitter"><img src="/themes/custom/ucb_premier/images/a2a/twitter-icon.svg" width="16" height="16" border="0" alt="twitter"></a></span> <div class="field field--name-field-like field--type-likes-dislikes field--label-above field__items"> <div class="like_dislike"> <div class="like"> <a rel="nofollow" class="use-ajax" href="/like-dislike/like/eyJlbnRpdHlfdHlwZSI6Im5vZGUiLCJlbnRpdHlfaWQiOiIxNTA1MCIsImZpZWxkX25hbWUiOiJmaWVsZF9saWtlIiwibGlrZXMiOiIzOTMiLCJkaXNsaWtlcyI6IjIifQ%3D%3D"></a> <span class="like-15050"> 393 Likes </span> </div> </div> <div id="like_dislike_status"></div> </div> Fri, 12 Jul 2024 06:49:46 +0000 Vandenbruaene Nathalie 15050 at Gene therapy: A new and innovative facility, new capabilities and new opportunities /innovation/magazine/detail/article/gene-therapy-a-new-and-innovative-facility-new-capabilities-and-new-opportunities <span>Gene therapy: A new and innovative facility, new capabilities and new opportunities </span> <div class="field field--name-field-newsroom-author-title field--type-string field--label-above field__items"> Jacques Marbehant, Manufacturing Engineering &amp; Health Safety &amp; Environment </div> <span><span lang about="/user/8671" typeof="schema:Person" property="schema:name" datatype content="Nathalie.Vandenbruaene@ucb.com">Vandenbruaene …</span></span> <span><time datetime="2022-03-08T08:33:52+01:00" title="Tuesday 8 March 2022 - 08:33">Tue 08/03/2022 - 08:33</time> </span> <div class="field field--name-field-newsroom-author-image field--type-entity-reference field--label-above field__items"> <article class="media media--type-image media--view-mode-default"> <div class="field field--name-image field--type-image field--label-hidden field__items"> <img loading="lazy" src="/sites/default/files/styles/ucb_header_image/public/2022-03/Jacques_Marbehant.jpg.webp?itok=HGj3b_ya" width="96" height="128" typeof="foaf:Image"> </div> </article> </div> <div class="field field--name-field-newsroom-content field--type-text-long field--label-above field__items"> <p><br> We are currently seeing within the industry a fundamental change in how we treat diseases. Therapies are moving from treating symptoms to disease modification. And we expect this trend to follow a trajectory from disease modification to finding a cure for certain diseases in defined patient populations.&nbsp;</p> <p>Gene therapy is a keep enabler of this trend. But producing the viral vectors that deliver these therapies can be challenging due to currently inefficient manufacturing processes and scarce high-cost third party development and manufacturing capacity.&nbsp;</p> <p><strong>Advancing our gene therapy journey&nbsp;</strong></p> <p>I’m excited to tell you about the new gene therapy facility ֳ is building, an innovative and environmentally sustainable facility that marks a significant investment in Belgium. Construction on our campus in Braine-l’Alleud, Wallonia, Belgium, is due to start in the second quarter of 2022, and we expect it to be operational by 2024. &nbsp;&nbsp;</p> <article data-quickedit-entity-id="media/36271" class="align-center media media--type-image media--view-mode-default"> <div class="field field--name-image field--type-image field--label-hidden field__items"> <img loading="lazy" src="/sites/default/files/styles/ucb_header_image/public/press_files/86c3e61bce9194c7_org.jpg.webp?itok=05nLhVJB" width="1086" height="609" alt="LR Impression 1 - Photo.jpg" typeof="foaf:Image"> </div> </article> <p><br> I am so enthusiastic about this significant next step in our gene therapy journey. It will see us enhance both our development and manufacturing capabilities, reinforcing our current gene therapy teams concentrated in Braine and Leuven in Belgium and Boston and Durham in the US. Our process and analytical development capabilities will take a significant leap forward, with the on-site experience giving us an unparalleled understanding of gene therapy products and processes.&nbsp;</p> <p>What’s more, the efficient clinical manufacturing capability will give us complete ownership of chemistry, manufacturing and controls (CMC) capabilities. It will make us more agile, so we can respond faster to new trends and opportunities, and more scalable to help meet the unmet needs of more patients. &nbsp;</p> <p><strong>Building gene therapy skills&nbsp;</strong></p> <p>Alongside building the bricks-and-mortar of our new facility, we will also continue to build on our skills and expertise in gene therapy. And gene therapy is an area that offers a wealth of opportunities. &nbsp;</p> <p>As well as opening new opportunities to current employees, the new facility will create more than 100 new and highly skilled jobs. That’s why we’re on the lookout for talented, inspired, daring and engaged individuals who, like us, have a passion for improving lives. &nbsp;</p> <p>So, join us! We have unique opportunities and exciting positions waiting for you! &nbsp;</p> <p>&nbsp;</p> </div> <div class="field field--name-field-newsroom-category field--type-entity-reference field--label-above field__items"> <a href="/taxonomy/term/1910" hreflang="en">innovation</a> </div> <div class="field field--name-field-newsroom-tags field--type-entity-reference field--label-above field__items"> <a href="/taxonomy/term/1831" hreflang="en">Gene therapy</a> <a href="/taxonomy/term/5661" hreflang="en">Braine-l'Alleud</a> <a href="/taxonomy/term/5671" hreflang="en">clinical manufacturing</a> </div> <div> <div class="comments-wrapper"> <div class="comment-area"> <h2 class="red">Leave a Comment</h2> <drupal-render-placeholder callback="comment.lazy_builders:renderForm" arguments="0=node&amp;1=13321&amp;2=field_newsroom_askexpert&amp;3=ask_expert" token="20pM-IfDJqzLS1OPa6Gkug3_432Pn5QXE8W_xzbW27E"></drupal-render-placeholder> <span class="toggle-form js-toggle-form"></span> </div> <div class="comment-wrap" data-comment-user-id="0" id="comment-39281"> <span class="block">Comment:</span> <div id="comment-39281" class="comment"> <span class="name-date"> Posted by <strong><span lang typeof="schema:Person" property="schema:name" datatype>Belaïd sekkali</span></strong>, 24 March 2022 </span> <div class="comment--body"> <div class="field field--name-comment-body field--type-text-long field--label-hidden field__items"> <p>Congratulations for the new GMP facility dedicated to GTMP manufacturing for clinical (and may be commercial?) use!</p> </div> </div> </div> <drupal-render-placeholder callback="comment.lazy_builders:renderLinks" arguments="0=39281&amp;1=default&amp;2=en&amp;3=" token="CsXCyKaD_21UJ3rSaFPsAwI5z8OvOuDkyqe7HyL48Pc"></drupal-render-placeholder> </div> </div> </div> <span class="a2a_kit a2a_kit_size_16 addtoany_list" data-a2a-url="/innovation/magazine/detail/article/gene-therapy-a-new-and-innovative-facility-new-capabilities-and-new-opportunities" data-a2a-title="Gene therapy: A new and innovative facility, new capabilities and new opportunities "><a class="a2a_dd addtoany_share" href="https://www.addtoany.com/share#url=https%3A%2F%2Fwww.ucb.com%2Finnovation%2Fmagazine%2Fdetail%2Farticle%2Fgene-therapy-a-new-and-innovative-facility-new-capabilities-and-new-opportunities&amp;title=Gene%20therapy%3A%20A%20new%20and%20innovative%20facility%2C%20new%20capabilities%20and%20new%20opportunities%20"></a><a class="a2a_button a2a_button_facebook"><img src="/themes/custom/ucb_premier/images/a2a/facebook-icon.svg" width="16" height="16" border="0" alt="linkedin"></a><a class="a2a_button a2a_button_linkedin"><img src="/themes/custom/ucb_premier/images/a2a/linkedin-icon.svg" width="16" height="16" border="0" alt="linkedin"></a><a class="a2a_button a2a_button_twitter"><img src="/themes/custom/ucb_premier/images/a2a/twitter-icon.svg" width="16" height="16" border="0" alt="twitter"></a></span> <div class="field field--name-field-like field--type-likes-dislikes field--label-above field__items"> <div class="like_dislike"> <div class="like"> <a rel="nofollow" class="use-ajax" href="/like-dislike/like/eyJlbnRpdHlfdHlwZSI6Im5vZGUiLCJlbnRpdHlfaWQiOiIxMzMyMSIsImZpZWxkX25hbWUiOiJmaWVsZF9saWtlIiwibGlrZXMiOiI2NjEiLCJkaXNsaWtlcyI6Ii0yMjYifQ%3D%3D"></a> <span class="like-13321"> 661 Likes </span> </div> </div> <div id="like_dislike_status"></div> </div> Tue, 08 Mar 2022 07:33:52 +0000 Vandenbruaene Nathalie 13321 at