Neupro? (Restless Legs Syndrome) Europe In Europe, Neupro? (rotigotine transdermal patch) is indicated for the symptomatic treatment of moderate to severe idiopathic Restless Legs Syndrome in adults. USA In the US, Neupro? (Rotigotine Transdermal System) is indicated for the treatment of moderate-to-severe primary Restless Legs Syndrome. Prescribing information Europe Prescribing information USA US prescribing information Neupro?